Antioxidant, Anticancer and Antimicrobial, Effects of Rubia cordifolia Aqueous Root Extract

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چکیده

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Anti-diarrheal and anti-inflammatory activities of aqueous extract of the aerial part of Rubia cordifolia

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Anticancer constituents from the roots of Rubia cordifolia L.

Activity-directed isolation of the methylene chloride fraction of the roots of Rubia cordifolia L. resulted in the identification of a new epoxymollugin (3) and eight known compounds (1, 2, 4-9). The structures of the compounds were elucidated from chemical and spectroscopic evidence. In addition, their topoisomerase I and II inhibitory activities and cytotoxicities were measured.

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This study was undertaken to investigate the possible effect of hydroalcoholic root extract of Rubia cordifolia against indomethacin-induced enterocolitis in rats. Male Wistar rats received vehicle or hydroalcoholic root extract of Rubia cordifolia (300 and 600 mg/kg) for 11 consecutive days. Enterocolitis was induced by subcutaneous administration of indomethacin (7.5 mg/kg) on 8(th) and 9(th)...

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ژورنال

عنوان ژورنال: Journal of Advances in Biology & Biotechnology

سال: 2016

ISSN: 2394-1081

DOI: 10.9734/jabb/2016/22625